Cytotoxic and Apoptotic Activity of the Novel Harmine Derivative ZC-14 in Sf9 Cells.

Harmine, one of many pure β-carboline alkaloids extracted from Peganum harmala L., displays broad spectrum however restricted insecticidal capability in opposition to many pests. So there’s an pressing have to synthesize novel derivatives with excessive effectivity. Within the current examine, a brand new artificial compound, [1-(2-naphthyl)-3-(2-thioxo-1,3,4-oxadiazol-5-yl) β-carboline] (ZC-14), confirmed a robust proliferation inhibition impact in opposition to the Spodoptera frugiperda Sf9 cell line in a dose-dependent method.

Concurrently, apoptosis induced by 7.5 μg/mL ZC-14 was confirmed with physiological and biochemical proof, together with typical apoptosis traits with shrinkage, apoptotic our bodies, nuclear condensation/fragmentation, a transparent DNA ladder, and a collection of apoptotic charges. As well as, mitochondria have been confirmed to be concerned in apoptosis induced by ZC-14 accompanied with the lack of mitochondrial membrane potential (Δψm), the discharge of cytochrome c from mitochondria into the cytosol and elevated expression of cleaved-caspase-3.

Nevertheless, harmine couldn’t induce apoptosis on the similar focus. In abstract, these knowledge indicated that compound ZC-14 has the next cytotoxicity than harmine in opposition to Sf9 cells. Apart from, it exhibited an anti-proliferative impact in Sf9 cells by way of inducing apoptosis by which the mitochondrial apoptotic pathway performs a vital position. Notably, the inhibition of ROS technology by the antioxidant N‑acetyl‑L‑cysteine considerably attenuated the luteolin‑induced lack of ΔΨm and actions of caspase‑3, ‑eight and ‑9. These knowledge steered that luteolin exerts its professional‑apoptotic motion partly by means of the p53‑dependent mitochondrial signaling pathway mediated by intracellular ROS, which offers a promising therapeutic candidate for sufferers with MDS.

 

The analysis of antioxidant and anticancer results of Lepidium Sativum Subsp Spinescens L. methanol extract on most cancers cells.

Lately, there’s an elevated analysis curiosity for vegetation that are pure sources of antioxidants. Lepidium sativum Subsp spinescens L., generally present in South West Asia, is a plant generally known as a wholesome dietary supply containing bio-molecules that carry anti-hypertensive, hypoglycemic, anti-asthmatic, antispasmodic, hepato-protective, chemoprotective, anti-inflammatory and anti-oxidant results. On this examine, we aimed to analyze the antioxidant content material and exercise of Lepidium sativum Subsp spinescens L. methanol extract on most cancers cells.

Methanol extract of dried Lepidium sativum Subsp spinescens L. was ready. Whole quantity of phenolic compounds was decided by Slinkard and Singleton technique utilizing Folin-Ciocalteu reagent. Whole flavonoid quantity was decided in response to Zhishen technique. Antioxidant exercise of the extract was evaluated by CUPRAC and ABTS radical scavenging exercise assays. Cytotoxic results of the plant extract on colon and endometrium most cancers cells, and human peripheral lymphocyte cells have been investigated in vitro by MTT and impartial purple assays.

Moreover, the plant extract was investigated for necrotic results by LDH assay; apoptotic exercise by DNA ladder fragmentation, ELISA and acridine orange/ethidium bromide staining; and genotoxic impact by comet assay strategies. Methanol extract of Lepidium sativum Subsp spinescens L. was discovered to have a excessive content material of phenolic and flavonoid compounds. The extract confirmed vital antioxidant exercise and likewise cytotoxic exercise on colon and endometrium most cancers cells in a concentration-dependent method. Apoptotic exercise and genotoxic results have been considerably elevated, particularly with 200 μg/ml concentrations at 48 hours incubation.

In conclusion, it was decided that the extract evaluated on this examine could possibly be a pure supply of antioxidants. Additional molecular research explaining chemo-preventive and chemotherapeutic results on most cancers cells are required to assist anticancer efficacy of the plant. Our knowledge indicated that isoaaptamine represents an fascinating drug lead within the battle in opposition to breast most cancers.

Cytotoxic and Apoptotic Activity of the Novel Harmine Derivative ZC-14 in Sf9 Cells.

Isoaaptamine Induces T-47D Cells Apoptosis and Autophagy by way of Oxidative Stress.

Aaptos is a genus of marine sponge which belongs to Suberitidae and is distributed in tropical and subtropical oceans. Bioactivity-guided fractionation of Aaptos sp. methanolic extract resulted within the isolation of aaptamine, demethyloxyaaptamine, and isoaaptamine. The cytotoxic exercise of the isolated compounds was evaluated revealing that isoaaptamine exhibited potent cytotoxic exercise in opposition to breast most cancers T-47D cells. In a concentration-dependent method, isoaaptamine inhibited the expansion of T-47D cells as indicated by short-(MTT) and long-term (colony formation) anti-proliferative assays.

The cytotoxic impact of isoaaptamine was mediated by means of apoptosis as indicated by DNA ladder formation, caspase-7 activation, XIAP inhibition and PARP cleavage. Transmission electron microscopy and flow cytometric analysis utilizing acridine orange dye indicated that isoaaptamine remedy could induce T-47D cells autophagy. Immunoblot assays demonstrated that isoaaptamine remedy vitally activated autophagy marker proteins resembling sort II LC-3. As well as, isoaaptamine remedy enhanced the activation of DNA injury (γH2AX) and ER stress-related proteins (IRE1 α and BiP).

Rubella virus RT PCR kit

RTq-H481-50R 50T
EUR 1155.6

Rubella virus PCR kit

PCR-H481-48R 50T
EUR 987.6

Rubella virus PCR kit

PCR-H481-96R 100T
EUR 1335.6

Rubella virus One-Step PCR kit

Oneq-H481-100R 100T
EUR 1932

Rubella virus One-Step PCR kit

Oneq-H481-150R 150T
EUR 2646

Rubella virus One-Step PCR kit

Oneq-H481-50R 50T
EUR 1410

Monkeypox Virus Real Time PCR Kit

PDPS-AR064 1 unit Ask for price
Description: Creative Biogene Monkeypox Virus Real Time PCR Kit is used for the detection of monkeypox Virus in serum or lesion exudate samples by using real time PCR systems. Monkeypox virus (MPV) is a double-stranded DNA, zoonotic virus and a species of the genus Orthopoxvirus in the family Poxviridae. It is one of the human orthopoxviruses that includes variola (VARV), cowpox (CPX), and vaccinia (VACV) viruses. The kit contains a specific ready-to-use system for the detection of the monkeypox Virus. Fluorescence is emitted and measured by the real time systems' optical unit during the PCR.

Monkeypox Virus Real Time PCR Kit

YJC70115NW-25T 25 tests/kit Ask for price
Description: The Bioperfectus Monkeypox Virus Real Time PCR Kit is an in vitro diagnostic test, based on real-time PCR technology, for the detection of DNA from the Monkeypox virus. Specimens can be obtained from human serum, lesion exudate samples and scab. BSL-2 facilities with standard BSL-2 work practices may be used for the test of t he Monkeypox virus.

Monkeypox Virus Real Time PCR Kit

ZD-0076-01 25 tests/kit Ask for price
Description: Monkeypox virus is the virus that causes the disease monkeypox in both humans and animals. Monkeypox virus is an Orthopoxvirus, a genus of the family Poxviridae that contains other viral species that target mammals. The virus is mainly found in tropical rainforest regions of central and West Africa. The primary route of infection is thought to be contact with the infected animals or their bodily fluids. The genome is not segmented and contains a single molecule of linear double-stranded DNA, 185000 nucleotides long. The Monkeypox Virus real time PCR Kit contains a specific ready-to-use system for the detection of the Monkeypox Virusthrough polymerase chain reaction (PCR) in the real-time PCR system. The master contains reagents and enzymes for the specific amplification of the Monkeypox Virus DNA. Fluorescence is emitted and measured by the real time systems ́ optical unit during the PCR. The detection of amplified Monkeypox Virus DNA fragment is performed in fluorimeter channel 530nm with the fluorescent quencher BHQ1. DNA extraction buffer is available in the kit and serum or lesion exudate samples are used for the extraction of the DNA. In addition, the kit contains a system to identify possible PCR inhibition by measuring the 560nm fluorescence of the internal control (IC). An external positive control defined as 1×10^7 copies/ml is supplied which allow the determination of the gene load.

Monkeypox Virus Real Time PCR Kit

ZD-0076-02 25 tests/kit Ask for price
Description: Monkeypox virus is the virus that causes the disease monkeypox in both humans and animals. Monkeypox virus is an Orthopoxvirus, a genus of the family Poxviridae that contains other viral species that target mammals. The virus is mainly found in tropical rainforest regions of central and West Africa. The primary route of infection is thought to be contact with the infected animals or their bodily fluids.The genome is not segmented and contains a single molecule of linear double-stranded DNA, 185000 nucleotides long.The Monkeypox Virus real time PCR Kit contains a specific ready-to-use system for the detection of the Monkeypox Virusthrough polymerase chain reaction (PCR) in the real-time PCR system. The master contains reagents and enzymes for the specific amplification of theMonkeypox VirusDNA. Fluorescence is emitted and measured by the real time systems ́ optical unit during the PCR. The detection of amplified Monkeypox Virus DNA fragment is performed in fluorimeter channelFAM with the fluorescent quencher BHQ1. DNA extraction buffer is available in the kit and serum or lesion exudate samples are used for the extraction of the DNA. In addition, the kit contains a system to identify possible PCR inhibition by measuring the HEX/VIC/JOE fluorescence of the internal control (IC). An external positive control defined as 1×107copies/ml is supplied which allow the determination of the gene load.

QPCR Kit RNA Rubella virus

MOL8312 EACH
EUR 788.88

Rubella virus protein

30-1344 1 ml
EUR 457.2
Description: Purified native Rubella virus protein (Grade III)

Rubella Virus Protein

abx670270-1mg 1 mg
EUR 1212

Rubella Virus Protein

abx670271-1mg 1 mg
EUR 2163.6

Rubella virus antibody

10R-R119a 1 mg
EUR 444
Description: Mouse monoclonal Antibody raised against Rubella virus

Rubella virus antibody

20-RG04 1 ml
EUR 440.4
Description: Goat polyclonal Rubella virus antibody

Rubella Virus Antibody

abx023129-1ml 1 ml
EUR 644.4

Rubella Virus E1 Mosaic

PR27125 500 ug
EUR 999.6

Rubella Virus Capsid C

PR27126 500 ug
EUR 999.6

Rubella virus E2 protein

30-1281 1 mg
EUR 1585.2
Description: Purified recombinant Rubella virus E2 protein

Rubella Virus E1 protein

80-1059 1 mg
EUR 2058
Description: Purified recombinant Rubella Virus E1 protein

Rubella Virus E2 Protein

abx060648-1mg 1 mg
EUR 2055.6

Rubella Virus E2 Protein

abx060649-1mg 1 mg
EUR 1713.6

Rubella Virus E2 Protein

20-abx260148
  • EUR 1062.00
  • EUR 410.40
  • EUR 1646.40
  • 0.5 mg
  • 100 ug
  • 1 mg

Rubella virus E2 protein

DAGA-498 1mg
EUR 3385.2

Rubella Virus E1 Antibody

abx022204-1mg 1 mg
EUR 718.8

Rubella Virus E1 Antibody

abx022205-1mg 1 mg
EUR 610.8

Rubella Virus E1 Antibody

abx022206-1mg 1 mg
EUR 610.8

Rubella virus antibody (HRP)

60-RG05 1 ml
EUR 480
Description: Goat polyclonal Rubella virus antibody (HRP) conjugated

Rubella Virus Antibody (HRP)

abx023126-1ml 1 ml
EUR 718.8

Rubella virus antibody (FITC)

60-RG04 1 ml
EUR 440.4
Description: Goat polyclonal Rubella virus antibody (FITC) conjugated

Rubella Virus Antibody (FITC)

abx023127-1ml 1 ml
EUR 661.2

Recombinant Rubella Virus E2

7-07861 100µg Ask for price

Recombinant Rubella Virus E2

7-07862 500µg Ask for price

Recombinant Rubella Virus E2

7-07863 1000µg Ask for price

Rubella Virus Capsid Protein

abx060645-1mg 1 mg
EUR 2180.4

Rubella Virus E1 protein [GST]

DAGA-499 1mg
EUR 4446

Rubella virus protein (Grade 1)

30-1330 1 ml
EUR 975.6
Description: Purified Native Rubella virus protein (Grade 1)

Rubella virus protein (Grade 2)

30-1331 1 mg
EUR 2018.4
Description: Purified Native Rubella virus protein (Grade 2)

Rubella Virus Capsid C protein

80-1058 100 ug
EUR 548.4
Description: Purified recombinant Rubella Virus Capsid C protein

Rubella Virus E1 Mosaic Protein

abx060646-1mg 1 mg
EUR 2214

Rubella Virus E1 Mosaic Protein

abx060647-1mg 1 mg
EUR 1796.4

Rubella Virus Capsid C Protein

20-abx260149
  • EUR 1062.00
  • EUR 410.40
  • EUR 1646.40
  • 0.5 mg
  • 100 ug
  • 1 mg

Rubella Virus E1 Mosaic Protein

20-abx260310
  • EUR 1062.00
  • EUR 410.40
  • EUR 1930.80
  • 0.5 mg
  • 100 ug
  • 1 mg

Recombinant Rubella Virus Rubella E1 Protein, GST, E.coli-1mg

QP13373-1mg 1mg
EUR 1513.2

Recombinant Rubella Virus Rubella E1 Protein, GST, E.coli-100ug

QP13373-100ug 100ug
EUR 261.6

Recombinant Rubella Virus Rubella E1 Protein, GST, E.coli-500ug

QP13373-500ug 500ug
EUR 795.6

Rat Rubella virus antibody IgG ELISA Kit

ERR0019 96Tests
EUR 625.2

Rat Rubella virus antibody IgA ELISA Kit

ERR0020 96Tests
EUR 625.2

Rat Rubella virus antibody IgM ELISA Kit

ERR0021 96Tests
EUR 625.2

Recombinant Rubella Virus Rubella Capsid Protein, GST, E.coli-1mg

QP13372-1mg 1mg
EUR 1273.2

Recombinant Rubella Virus Rubella E2 Protein, Untagged, E.coli-1mg

QP13374-1mg 1mg
EUR 1273.2

Human Rubella Virus IgG Antibody ELISA Kit

abx053898-96tests 96 tests
EUR 801.6

Human Rubella Virus IgM Antibody ELISA Kit

abx054089-96tests 96 tests
EUR 801.6

Mouse Rubella virus antibody IgG ELISA Kit

EMR0019 96Tests
EUR 625.2

Mouse Rubella virus antibody IgA ELISA Kit

EMR0020 96Tests
EUR 625.2

Mouse Rubella virus antibody IgM ELISA Kit

EMR0021 96Tests
EUR 625.2

Human Rubella Virus IgM Antibody ELISA Kit

abx364857-96tests 96 tests
EUR 548.4

Human Rubella Virus IgG Antibody ELISA Kit

abx364858-96tests 96 tests
EUR 548.4

Human Rubella virus antibody IgG ELISA Kit

EHR0019 96Tests
EUR 625.2

Human Rubella virus antibody IgA ELISA Kit

EHR0020 96Tests
EUR 625.2

Human Rubella virus antibody IgM ELISA Kit

EHR0021 96Tests
EUR 625.2

Bovine Rubella Virus Antibody IgG ELSA KIT

QY-E60087 96T
EUR 511.2

Recombinant Rubella Virus E1 Mosaic

7-07858 100µg Ask for price

Recombinant Rubella Virus E1 Mosaic

7-07859 500µg Ask for price

Recombinant Rubella Virus E1 Mosaic

7-07860 1000µg Ask for price

Recombinant Rubella Virus Capsid C

7-07864 100µg Ask for price

Recombinant Rubella Virus Capsid C

7-07865 500µg Ask for price

Recombinant Rubella Virus Capsid C

7-07866 1000µg Ask for price

Recombinant Rubella Virus Rubella Capsid Protein, GST, E.coli-100ug

QP13372-100ug 100ug
EUR 261.6

Recombinant Rubella Virus Rubella Capsid Protein, GST, E.coli-500ug

QP13372-500ug 500ug
EUR 795.6

Recombinant Rubella Virus Rubella E2 Protein, Untagged, E.coli-100ug

QP13374-100ug 100ug
EUR 261.6

Recombinant Rubella Virus Rubella E2 Protein, Untagged, E.coli-500ug

QP13374-500ug 500ug
EUR 795.6

Rubella virus E2 Recombinant Protein

53-354 0.01 mg
EUR 714.3
Description: Rubella virus E2 Recombinant Protein

Rubella virus E1 Recombinant Protein

53-355 0.01 mg
EUR 714.3
Description: Rubella virus E1 Recombinant Protein

Rubella virus E2 recombinant antigen

00216-V-01mg 0,1 mg
EUR 321
Description: Rubella virus E2 recombinant antigen a.a. 31-105.

Rubella virus E2 recombinant antigen

00216-V-1000ug 1000 ug
EUR 1539
Description: Rubella virus E2 recombinant antigen a.a. 31-105.

Rubella virus E1 recombinant antigen

8806 100 ug
EUR 529.8
Description: This is Rubella virus E1 recombinant antigen for ELISA,WB.

Rubella virus E2 recombinant antigen

8807 100 ug
EUR 529.8
Description: This is Rubella virus E2 recombinant antigen for ELISA,WB.

Recombinant Rubella Virus E2 Protein

DAG514 1mg
EUR 1537.2

Human Rubella Virus (RV) IgG Rapid Test Kit

abx092097-20tests 20 tests
EUR 260.4

Rubella Virus Capsid Protein Antibody

abx022208-1mg 1 mg
EUR 610.8

Recombinant Rubella Virus Capsid (33 kDa)

DAG494 1mg
EUR 1731.6

Goat Rubella virus antibody IgG ELSA KIT ELISA Kit

EGTR0019 96Tests
EUR 625.2

Goat Rubella virus antibody IgA ELSA KIT ELISA Kit

EGTR0020 96Tests
EUR 625.2

Goat Rubella virus antibody IgM ELSA KIT ELISA Kit

EGTR0021 96Tests
EUR 625.2

Recombinant (E.Coli) Rubella Virus E2 protein

RP-1414 100 ug
EUR 343.2

Rabbit Rubella virus antibody IgG ELSA KIT ELISA Kit

ERTR0019 96Tests
EUR 625.2

Rabbit Rubella virus antibody IgA ELSA KIT ELISA Kit

ERTR0020 96Tests
EUR 625.2

Rabbit Rubella virus antibody IgM ELSA KIT ELISA Kit

ERTR0021 96Tests
EUR 625.2

Bovine Rubella virus antibody IgG ELSA KIT ELISA Kit

EBR0019 96Tests
EUR 625.2

Bovine Rubella virus antibody IgA ELSA KIT ELISA Kit

EBR0020 96Tests
EUR 625.2

Bovine Rubella virus antibody IgM ELSA KIT ELISA Kit

EBR0021 96Tests
EUR 625.2

Canine Rubella virus antibody IgG ELSA KIT ELISA Kit

ECR0019 96Tests
EUR 625.2

Canine Rubella virus antibody IgA ELSA KIT ELISA Kit

ECR0020 96Tests
EUR 625.2

Canine Rubella virus antibody IgM ELSA KIT ELISA Kit

ECR0021 96Tests
EUR 625.2

Goat polyclonal antibody for Rubella virus

504 1 ml
EUR 373.2
Description: This is HRP conjugated goat polyclonal antibody against Rubella virus virions for WB, ELISA.

Goat polyclonal antibody for Rubella virus

1701 1 ml
EUR 327.53
Description: This is goat polyclonal antibody against Rubella virus virions for WB, ELISA.

Goat polyclonal antibody for Rubella virus

1703 1 ml
EUR 347.1
Description: This is FITC conjugated goat polyclonal antibody against Rubella virus virions for WB, ELISA.

Goat polyclonal antibody for Rubella virus

1707 1 ml
EUR 347.1
Description: This is Biotin conjugated goat polyclonal antibody against Rubella virus virions for WB, ELISA.

Porcine Rubella virus antibody IgG ELSA KIT ELISA Kit

EPR0019 96Tests
EUR 625.2

Porcine Rubella virus antibody IgA ELSA KIT ELISA Kit

EPR0020 96Tests
EUR 625.2

Porcine Rubella virus antibody IgM ELSA KIT ELISA Kit

EPR0021 96Tests
EUR 625.2

Rubella virus E1 mosaic recombinant antigen

00215-V-01mg 0,1 mg
EUR 321
Description: Rubella virus E1 mosaic recombinant antigen a.a. 157-176/374-390/213-239.

Rubella virus E1 mosaic recombinant antigen

00215-V-1000ug 1000 ug
EUR 1539
Description: Rubella virus E1 mosaic recombinant antigen a.a. 157-176/374-390/213-239.

Rubella virus capsid (C) recombinant antigen

00217-V-01mg 0,1 mg
EUR 321
Description: Rubella virus capsid (C) recombinant antigen a.a. 1-123.

Rubella virus capsid (C) recombinant antigen

00217-V-1000ug 1000 ug
EUR 1539
Description: Rubella virus capsid (C) recombinant antigen a.a. 1-123.

Anserine Rubella virus antibody IgG ELSA KIT ELISA Kit

EAR0019 96Tests
EUR 625.2

Anserine Rubella virus antibody IgA ELSA KIT ELISA Kit

EAR0020 96Tests
EUR 625.2

Anserine Rubella virus antibody IgM ELSA KIT ELISA Kit

EAR0021 96Tests
EUR 625.2

Mouse Anti Rubella Virus Monoclonal Antibody

DMABT-51535MR 0.2 mg
EUR 795.6

Mouse Rubella Virus Antibody IgG(RV-IgG )ELSA KIT

QY-E21685 96T
EUR 448.8

Recombinant Rubella Virus E1 mosaic (32 kDa)

DAG507 1mg
EUR 1725.6

Guinea Pig Rubella virus antibody IgG ELSA KIT ELISA Kit

EGR0019 96Tests
EUR 625.2

Guinea Pig Rubella virus antibody IgA ELSA KIT ELISA Kit

EGR0020 96Tests
EUR 625.2

Guinea Pig Rubella virus antibody IgM ELSA KIT ELISA Kit

EGR0021 96Tests
EUR 625.2

Rubella virus E2 recombinant antigen a.a. 31-105.

00216-V-100ugvial 100 ug/vial
EUR 150
Description: Rubella virus E2 recombinant antigen a.a. 31-105.

Mouse antibody for Rubella virus E1 glycoprotein

1712 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Rubella virus E1 glycoprotein for WB, ELISA.

Mouse antibody for Rubella virus E1 glycoprotein

1714 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Rubella virus E1 glycoprotein for WB, ELISA.

Mouse antibody for Rubella virus E1 glycoprotein

1715 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Rubella virus E1 glycoprotein for WB, ELISA.

Mouse antibody for Rubella virus E2 glycoprotein

1717 100 ug
EUR 386.26
Description: This is purified Mouse monoclonal antibody against Rubella virus E2 glycoprotein for WB, ELISA.

Recombinant Rubella Virus E1 Mosaic, His-tagged

DAG488 mg
EUR 1452

Recombinant (E.Coli) Rubella Virus E1 Mosaic protein

RP-1413 100 ug
EUR 343.2

Recombinant (E.Coli) Rubella Virus Capsid C protein

RP-1415 100 ug
EUR 343.2

QPCR Kit RNA Rubella virusMmix

MOL8314 EACH
EUR 1010.04

Rubella virus (HPV77 strain) proteins/antigens extract

RUBL15-N-500 0.5 ml
EUR 388.8

Rubella virus capsid (C) recombinant antigen a.a. 1-123.

00217-V-100ugvial 100 ug/vial
EUR 150
Description: Rubella virus capsid (C) recombinant antigen a.a. 1-123.

Mouse Anti Rubella Virus Capsid Protein Monoclonal Antibody

DMABT-51537MR 0.2 mg
EUR 920.4

Mouse Anti Rubella Virus Glycoprotein E1 Monoclonal Antibody

DMABT-51538MR 0.2 mg
EUR 795.6

Mouse Anti Rubella Virus Glycoprotein E2 Monoclonal Antibody

DMABT-51540MR 0.2 mg
EUR 920.4

Rubella virus E1 mosaic recombinant antigen a.a. 157-176/374-390/213-239.

00215-V-100ugvial 100 ug/vial
EUR 150
Description: Rubella virus E1 mosaic recombinant antigen a.a. 157-176/374-390/213-239.

RealScreen Rubella IgG ELISA Kit

EL030-096 96T
EUR 999.6

RealScreen Rubella IgM ELISA Kit

EL031-096 96T
EUR 854.4

Human Cytomegalovirus, Toxoplasma, Rubella, Herpes simplex virus type II IgM Rapid Test Kit

abx092077-20tests 20 tests
EUR 410.4

Rubella ELISA Kit

55R-RB025G 96 wells
EUR 361.2
Description: ELISA kit for detection of Rubella in the research laboratory

0.2ML CLEAR STRIP CAPS FOR REAL TIME PCR

PCR-2CP-RT-C 125/pk
EUR 267.6
Description: PCR Plates & Tubes; PCR Strip Tubes and Strip Caps - Axygen

Rubella IgG ELISA Kit

E4666-100 each
EUR 646.8

Rubella IgM ELISA Kit

E4667-100 each
EUR 646.8

Human Lung Cancer PCR Primer Library

HLUCPL-I 1 set
EUR 657.6

Human Schwann Cell PCR Primer Library

HSCH-I 1 set
EUR 657.6

Novel Coronavirus COVID-19 (2019-nCoV) Real Time RT-PCR Kit

RR-0478-02 25 tests/kit
EUR 1189.2
Description: Novel Coronavirus (2019-nCoV) Real Time RT-PCR Kit is used for the qualitative detection of a novel coronavirus, which was identified in 2019 at Wuhan City, Hubei Province, China, in upper respiratory tract specimens (nasopharyngeal extracts, deep cough sputum, etc.) and lower respiratory tract specimens (alveoli irrigation fluid, etc.) by real time PCR systems.

Rat Rubella IgG ELISA Kit

QY-E11851 96T
EUR 448.8

Rubella 2-42 Protein

abx069921-1mg 1 mg
EUR 610.8

Rabbit Rubella IgG

QY-E30313 96T
EUR 448.8

Rubella BR2S Antigen

30-1979 1 mg
EUR 1524

Rubella 2-6 Protein

abx069923-1mg 1 mg
EUR 610.8

Rubella IgM MAX Protein

abx160034-1mg 1 mg
EUR 4202.4

AzuraQuant cDNA Synthesis Kit - 100 Reactions

AZ-1996 100 Reactions
EUR 446.4

Axygen Polyester ultra clear sealing film for real time PCR

AXY2152 PK100
EUR 382.8

Eztime Real - time PCRPremix 2x,Taqman

FYT105-100P 100 Preps 1.25 ml Ask for price

Human Rubella IgG ELISA Kit (Direct EIA)

EK7082 96wells/kit, with removable strips.
EUR 573.6

Human Rubella IgM ELISA Kit (Direct EIA)

EK7083 96wells/kit, with removable strips.
EUR 573.6

AzuraQuant cDNA Synthesis Kit - 25 Reactions

AZ-1995 25 Reactions
EUR 183.6

Eco 48 Real Time PCR system including software and loading dock

MOL6348 EACH
EUR 18466.8

Eztime Real - time PCRPremix 2x,SYBR Green

FYT103-100P 100 Preps 1.25 ml Ask for price

Eztime Real - time PCRPremix 2x,SYBR Green

FYT103-400P 400 Preps 1.25 ml x 4 Ask for price

Eztime Real - time PCRPremix 2x,Taqman, ROX

FYT105-400P 400 Preps 1.25 ml x 4 Ask for price

Eztime Real - time PCRPremix 2x,Taqman, ROX

FYT106-100P 100 Preps 1.25 ml Ask for price

Eztime Real - time PCRPremix 2x,SYBRGreen , ROX

FYT104-100P 100 Preps 1.25 ml Ask for price

Eztime Real - time PCRPremix 2x,SYBRGreen , ROX

FYT104-400P 400 Preps 1.25 ml x 4 Ask for price

RV (Rubella Antibody IgG) ELISA test

30 96T/Box Ask for price
Description: ELISA based test for quantitative detection of RV (Rubella Antibody IgG)

RV (Rubella Antibody IgM) ELISA test

31 96T/Box Ask for price
Description: ELISA based test for quantitative detection of RV (Rubella Antibody IgM)

Furthermore, the usage of isoaaptamine resulted in a major enhance within the technology of reactive oxygen species (ROS) as well as within the disruption of mitochondrial membrane potential (MMP). The pretreatment of T-47D cells with an ROS scavenger, N-acetyll-cysteine (NAC), attenuated the apoptosis and MMP disruption induced by isoaaptamine as much as 90%, and these results have been mediated by the disruption of nuclear issue erythroid 2-related issue 2 (Nrf 2)/p62 pathway. Taken collectively, these findings steered that the cytotoxic impact of isoaaptamine is related to the induction of apoptosis and autophagy by means of oxidative stress.

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