Cytotoxic and Apoptotic Activity of the Novel Harmine Derivative ZC-14 in Sf9 Cells.

Harmine, one of many pure β-carboline alkaloids extracted from Peganum harmala L., displays broad spectrum however restricted insecticidal capability in opposition to many pests. So there’s an pressing have to synthesize novel derivatives with excessive effectivity. Within the current examine, a brand new artificial compound, [1-(2-naphthyl)-3-(2-thioxo-1,3,4-oxadiazol-5-yl) β-carboline] (ZC-14), confirmed a robust proliferation inhibition impact in opposition to the Spodoptera frugiperda Sf9 cell line in a dose-dependent method.

Concurrently, apoptosis induced by 7.5 μg/mL ZC-14 was confirmed with physiological and biochemical proof, together with typical apoptosis traits with shrinkage, apoptotic our bodies, nuclear condensation/fragmentation, a transparent DNA ladder, and a collection of apoptotic charges. As well as, mitochondria have been confirmed to be concerned in apoptosis induced by ZC-14 accompanied with the lack of mitochondrial membrane potential (Δψm), the discharge of cytochrome c from mitochondria into the cytosol and elevated expression of cleaved-caspase-3.

Nevertheless, harmine couldn’t induce apoptosis on the similar focus. In abstract, these knowledge indicated that compound ZC-14 has the next cytotoxicity than harmine in opposition to Sf9 cells. Apart from, it exhibited an anti-proliferative impact in Sf9 cells by way of inducing apoptosis by which the mitochondrial apoptotic pathway performs a vital position. Notably, the inhibition of ROS technology by the antioxidant N‑acetyl‑L‑cysteine considerably attenuated the luteolin‑induced lack of ΔΨm and actions of caspase‑3, ‑eight and ‑9. These knowledge steered that luteolin exerts its professional‑apoptotic motion partly by means of the p53‑dependent mitochondrial signaling pathway mediated by intracellular ROS, which offers a promising therapeutic candidate for sufferers with MDS.

 

The analysis of antioxidant and anticancer results of Lepidium Sativum Subsp Spinescens L. methanol extract on most cancers cells.

Lately, there’s an elevated analysis curiosity for vegetation that are pure sources of antioxidants. Lepidium sativum Subsp spinescens L., generally present in South West Asia, is a plant generally known as a wholesome dietary supply containing bio-molecules that carry anti-hypertensive, hypoglycemic, anti-asthmatic, antispasmodic, hepato-protective, chemoprotective, anti-inflammatory and anti-oxidant results. On this examine, we aimed to analyze the antioxidant content material and exercise of Lepidium sativum Subsp spinescens L. methanol extract on most cancers cells.

Methanol extract of dried Lepidium sativum Subsp spinescens L. was ready. Whole quantity of phenolic compounds was decided by Slinkard and Singleton technique utilizing Folin-Ciocalteu reagent. Whole flavonoid quantity was decided in response to Zhishen technique. Antioxidant exercise of the extract was evaluated by CUPRAC and ABTS radical scavenging exercise assays. Cytotoxic results of the plant extract on colon and endometrium most cancers cells, and human peripheral lymphocyte cells have been investigated in vitro by MTT and impartial purple assays.

Moreover, the plant extract was investigated for necrotic results by LDH assay; apoptotic exercise by DNA ladder fragmentation, ELISA and acridine orange/ethidium bromide staining; and genotoxic impact by comet assay strategies. Methanol extract of Lepidium sativum Subsp spinescens L. was discovered to have a excessive content material of phenolic and flavonoid compounds. The extract confirmed vital antioxidant exercise and likewise cytotoxic exercise on colon and endometrium most cancers cells in a concentration-dependent method. Apoptotic exercise and genotoxic results have been considerably elevated, particularly with 200 μg/ml concentrations at 48 hours incubation.

In conclusion, it was decided that the extract evaluated on this examine could possibly be a pure supply of antioxidants. Additional molecular research explaining chemo-preventive and chemotherapeutic results on most cancers cells are required to assist anticancer efficacy of the plant. Our knowledge indicated that isoaaptamine represents an fascinating drug lead within the battle in opposition to breast most cancers.

Cytotoxic and Apoptotic Activity of the Novel Harmine Derivative ZC-14 in Sf9 Cells.

Isoaaptamine Induces T-47D Cells Apoptosis and Autophagy by way of Oxidative Stress.

Aaptos is a genus of marine sponge which belongs to Suberitidae and is distributed in tropical and subtropical oceans. Bioactivity-guided fractionation of Aaptos sp. methanolic extract resulted within the isolation of aaptamine, demethyloxyaaptamine, and isoaaptamine. The cytotoxic exercise of the isolated compounds was evaluated revealing that isoaaptamine exhibited potent cytotoxic exercise in opposition to breast most cancers T-47D cells. In a concentration-dependent method, isoaaptamine inhibited the expansion of T-47D cells as indicated by short-(MTT) and long-term (colony formation) anti-proliferative assays.

The cytotoxic impact of isoaaptamine was mediated by means of apoptosis as indicated by DNA ladder formation, caspase-7 activation, XIAP inhibition and PARP cleavage. Transmission electron microscopy and flow cytometric analysis utilizing acridine orange dye indicated that isoaaptamine remedy could induce T-47D cells autophagy. Immunoblot assays demonstrated that isoaaptamine remedy vitally activated autophagy marker proteins resembling sort II LC-3. As well as, isoaaptamine remedy enhanced the activation of DNA injury (γH2AX) and ER stress-related proteins (IRE1 α and BiP).

Rubella virus RT PCR kit

RTq-H481-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Rubella virus .

Rubella virus RT PCR kit

RTq-H481-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Rubella virus .

Rubella virus RT PCR kit

RTq-H481-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Rubella virus .

Rubella virus PCR kit

PCR-H481-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Rubella virus

Rubella virus PCR kit

PCR-H481-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Rubella virus

MDV Real-Time PCR Kit

PD65-06 96t
EUR 1553.6
Description: Please check the datasheet of MDV Real-Time PCR Kit before using the test.

ALV Real-Time PCR Kit

PD65-15 96t
EUR 1724.4
Description: Please check the datasheet of ALV Real-Time PCR Kit before using the test.

hsa-mir-521 Real-time RT-PCR Detection Kit

20-abx097600
  • EUR 551.00
  • EUR 787.00
  • EUR 398.00
  • 100 rxns
  • 200 rxns
  • 50 rxns
  • Shipped within 3 weeks.

Novel Coronavirus COVID-19 (2019-nCoV) Real Time RT-PCR Kit

RR-0478-02 25 tests/kit
EUR 991
  • For use with PE5700, MJ-Opticon & other single color systems, ABI7000, ABI7300, ABI7500, ABI7900, ABI StepOne, StepOne plus, MJ-Opticon2, MJ-chromo4, MX3000P, MX3005P, Smart Cycler II, Rotor-Gene 6000, LightCycler 480, CFX 96, Life 96, Slan 96, iCycl
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Description: Novel Coronavirus (2019-nCoV) Real Time RT-PCR Kit is used for the qualitative detection of a novel coronavirus, which was identified in 2019 at Wuhan City, Hubei Province, China, in upper respiratory tract specimens (nasopharyngeal extracts, deep cough sputum, etc.) and lower respiratory tract specimens (alveoli irrigation fluid, etc.) by real time PCR systems.

Rubella virus One-Step PCR kit

Oneq-H481-100R 100T
EUR 933
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Rubella virus.

Rubella virus One-Step PCR kit

Oneq-H481-150R 150T
EUR 1060.6
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Rubella virus.

Rubella virus One-Step PCR kit

Oneq-H481-50R 50T
EUR 751.75
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Description: Real Time PCR Kit is a screening assay for a rapid and accurate detection of Rubella virus.

hsa-mir-521 Real-Time RT-PCR Detection and U6 Calibration Kit

20-abx097601
  • EUR 732.00
  • EUR 1038.00
  • EUR 523.00
  • 100 rxns
  • 200 rxns
  • 50 rxns
  • Shipped within 3 weeks.

0,1ML THIN WALL TUBES 8 PER STRIP. CLEAR & REAL TIME STRIP CAPS

PCR-0108-LP-RT-C 125/pk
EUR 709
Description: PCR Plates & Tubes; PCR Strip Tubes and Strip Caps - Axygen

0,1ML THIN WALL TUBES 8 PER STRIP. WHITE & REAL TIME STRIP CAPS

PCR-0108-LP-RT-W 125/pk
EUR 770
Description: PCR Plates & Tubes; PCR Strip Tubes and Strip Caps - Axygen

Virus Zika RT PCR kit

RTq-H434-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Virus Zika .

Virus Zika RT PCR kit

RTq-H434-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Virus Zika .

Virus Zika RT PCR kit

RTq-H434-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Virus Zika .

Dengue virus RT PCR kit

RTq-H451-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Dengue virus .

Dengue virus RT PCR kit

RTq-H451-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Dengue virus .

Dengue virus RT PCR kit

RTq-H451-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Dengue virus .

Chikungunya virus RT PCR kit

RTq-H525-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Chikungunya virus .

Chikungunya virus RT PCR kit

RTq-H525-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Chikungunya virus .

Chikungunya virus RT PCR kit

RTq-H525-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Chikungunya virus .

Measles Virus RT PCR kit

RTq-H639-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Measles Virus .

Measles Virus RT PCR kit

RTq-H639-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Measles Virus .

Measles Virus RT PCR kit

RTq-H639-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Measles Virus .

Mumps Virus RT PCR kit

RTq-H640-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Mumps Virus .

Mumps Virus RT PCR kit

RTq-H640-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Mumps Virus .

Mumps Virus RT PCR kit

RTq-H640-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Mumps Virus .

Uukuniemi virus RT PCR kit

RTq-V056-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Uukuniemi virus .

Uukuniemi virus RT PCR kit

RTq-V056-150R 150T
EUR 701
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Description: A Real-Time PCR kit for detection of Uukuniemi virus .

Uukuniemi virus RT PCR kit

RTq-V056-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Uukuniemi virus .

Reticuloendotheliosis virus RT PCR kit

RTq-V061-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Reticuloendotheliosis virus .

Reticuloendotheliosis virus RT PCR kit

RTq-V061-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Reticuloendotheliosis virus .

Reticuloendotheliosis virus RT PCR kit

RTq-V061-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Reticuloendotheliosis virus .

Distemper virus RT PCR kit

RTq-V111-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Distemper virus .

Distemper virus RT PCR kit

RTq-V111-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Distemper virus .

Distemper virus RT PCR kit

RTq-V111-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Distemper virus .

Pseudorabies Virus RT PCR kit

RTq-V123-100D 100T
EUR 628.5
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Description: A Real-Time PCR kit for detection of Pseudorabies Virus .

Pseudorabies Virus RT PCR kit

RTq-V123-150D 150T
EUR 701
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Description: A Real-Time PCR kit for detection of Pseudorabies Virus .

Pseudorabies Virus RT PCR kit

RTq-V123-50D 50T
EUR 532.8
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Description: A Real-Time PCR kit for detection of Pseudorabies Virus .

Cowpox virus RT PCR kit

RTq-V173-100D 100T
EUR 628.5
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Description: A Real-Time PCR kit for detection of Cowpox virus .

Cowpox virus RT PCR kit

RTq-V173-150D 150T
EUR 701
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Description: A Real-Time PCR kit for detection of Cowpox virus .

Cowpox virus RT PCR kit

RTq-V173-50D 50T
EUR 532.8
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Description: A Real-Time PCR kit for detection of Cowpox virus .

Akabane virus RT PCR kit

RTq-V267-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Akabane virus .

Akabane virus RT PCR kit

RTq-V267-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Akabane virus .

Akabane virus RT PCR kit

RTq-V267-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Akabane virus .

Irido virus RT PCR kit

RTq-V288-100D 100T
EUR 628.5
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Description: A Real-Time PCR kit for detection of Irido virus .

Irido virus RT PCR kit

RTq-V288-150D 150T
EUR 701
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Description: A Real-Time PCR kit for detection of Irido virus .

Irido virus RT PCR kit

RTq-V288-50D 50T
EUR 532.8
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Description: A Real-Time PCR kit for detection of Irido virus .

Mourilyan virus RT PCR kit

RTq-V291-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Mourilyan virus .

Mourilyan virus RT PCR kit

RTq-V291-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Mourilyan virus .

Mourilyan virus RT PCR kit

RTq-V291-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Mourilyan virus .

Schmallenberg virus RT PCR kit

RTq-V319-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Schmallenberg virus .

Schmallenberg virus RT PCR kit

RTq-V319-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Schmallenberg virus .

Schmallenberg virus RT PCR kit

RTq-V319-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Schmallenberg virus .

Ectromelia virus RT PCR kit

RTq-V330-100D 100T
EUR 628.5
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Description: A Real-Time PCR kit for detection of Ectromelia virus .

Ectromelia virus RT PCR kit

RTq-V330-150D 150T
EUR 701
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Description: A Real-Time PCR kit for detection of Ectromelia virus .

Ectromelia virus RT PCR kit

RTq-V330-50D 50T
EUR 532.8
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Description: A Real-Time PCR kit for detection of Ectromelia virus .

K Virus RT PCR kit

RTq-V365-100D 100T
EUR 628.5
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Description: A Real-Time PCR kit for detection of K Virus .

K Virus RT PCR kit

RTq-V365-150D 150T
EUR 701
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Description: A Real-Time PCR kit for detection of K Virus .

K Virus RT PCR kit

RTq-V365-50D 50T
EUR 532.8
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Description: A Real-Time PCR kit for detection of K Virus .

Sialodacryoadenitis virus RT PCR kit

RTq-V370-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Sialodacryoadenitis virus .

Sialodacryoadenitis virus RT PCR kit

RTq-V370-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Sialodacryoadenitis virus .

Sialodacryoadenitis virus RT PCR kit

RTq-V370-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Sialodacryoadenitis virus .

Sendai virus RT PCR kit

RTq-V374-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Sendai virus .

Sendai virus RT PCR kit

RTq-V374-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Sendai virus .

Sendai virus RT PCR kit

RTq-V374-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Sendai virus .

Junin Virus RT PCR kit

RTq-V388-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Junin Virus .

Junin Virus RT PCR kit

RTq-V388-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Junin Virus .

Junin Virus RT PCR kit

RTq-V388-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Junin Virus .

Machupo Virus RT PCR kit

RTq-V389-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Machupo Virus .

Machupo Virus RT PCR kit

RTq-V389-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Machupo Virus .

Machupo Virus RT PCR kit

RTq-V389-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Machupo Virus .

Lassa virus RT PCR kit

RTq-V390-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Lassa virus .

Lassa virus RT PCR kit

RTq-V390-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Lassa virus .

Lassa virus RT PCR kit

RTq-V390-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Lassa virus .

Guanarito virus RT PCR kit

RTq-V391-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Guanarito virus .

Guanarito virus RT PCR kit

RTq-V391-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Guanarito virus .

Guanarito virus RT PCR kit

RTq-V391-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Guanarito virus .

Sabia Virus RT PCR kit

RTq-V392-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Sabia Virus .

Sabia Virus RT PCR kit

RTq-V392-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Sabia Virus .

Sabia Virus RT PCR kit

RTq-V392-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Sabia Virus .

Ecephalomyocarditis virus RT PCR kit

RTq-V394-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Ecephalomyocarditis virus .

Ecephalomyocarditis virus RT PCR kit

RTq-V394-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Ecephalomyocarditis virus .

Ecephalomyocarditis virus RT PCR kit

RTq-V394-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Ecephalomyocarditis virus .

Visna virus RT PCR kit

RTq-V634-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Visna virus .

Visna virus RT PCR kit

RTq-V634-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Visna virus .

Visna virus RT PCR kit

RTq-V634-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Visna virus .

Swinepox virus RT PCR kit

RTq-V727-100D 100T
EUR 628.5
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Description: A Real-Time PCR kit for detection of Swinepox virus .

Swinepox virus RT PCR kit

RTq-V727-150D 150T
EUR 701
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Description: A Real-Time PCR kit for detection of Swinepox virus .

Swinepox virus RT PCR kit

RTq-V727-50D 50T
EUR 532.8
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Description: A Real-Time PCR kit for detection of Swinepox virus .

Kemerovo virus RT PCR kit

RTq-VH057-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Kemerovo virus .

Kemerovo virus RT PCR kit

RTq-VH057-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Kemerovo virus .

Kemerovo virus RT PCR kit

RTq-VH057-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Kemerovo virus .

Lipovnik virus RT PCR kit

RTq-VH058-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Lipovnik virus .

Lipovnik virus RT PCR kit

RTq-VH058-150R 150T
EUR 877.9
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Lipovnik virus .

Lipovnik virus RT PCR kit

RTq-VH058-50R 50T
EUR 631.4
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Lipovnik virus .

Rabies Virus RT PCR kit

RTq-VH113-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Rabies Virus .

Rabies Virus RT PCR kit

RTq-VH113-150R 150T
EUR 877.9
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Rabies Virus .

Rabies Virus RT PCR kit

RTq-VH113-50R 50T
EUR 631.4
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Rabies Virus .

Nipah virus RT PCR kit

RTq-VH139-100R 100T
EUR 776.4
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Nipah virus .

Nipah virus RT PCR kit

RTq-VH139-150R 150T
EUR 877.9
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Nipah virus .

Nipah virus RT PCR kit

RTq-VH139-50R 50T
EUR 631.4
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Nipah virus .

Norwalk virus RT PCR kit

RTq-VH262-100R 100T
EUR 776.4
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Norwalk virus .

Norwalk virus RT PCR kit

RTq-VH262-150R 150T
EUR 877.9
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Description: A Real-Time PCR kit for detection of Norwalk virus .

Norwalk virus RT PCR kit

RTq-VH262-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Norwalk virus .

Seoul virus RT PCR kit

RTq-VH395-100R 100T
EUR 776.4
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Description: A Real-Time PCR kit for detection of Seoul virus .

Seoul virus RT PCR kit

RTq-VH395-150R 150T
EUR 877.9
  • Contact us in order to know the reactivity of the kit.
Description: A Real-Time PCR kit for detection of Seoul virus .

Seoul virus RT PCR kit

RTq-VH395-50R 50T
EUR 631.4
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Description: A Real-Time PCR kit for detection of Seoul virus .

dsGreen for Real-Time PCR, 100×, 100 uL

11010 100 uL
EUR 59

dsGreen for Real-Time PCR, 100×, 2 mL

61010 2 mL
EUR 363

dsGreen for Real-Time PCR, 100×, 1.5 mL

51010 1.5 mL
EUR 331

dsGreen for Real-Time PCR, 100×, 1 mL

41010 1 mL
EUR 249

dsGreen for Real-Time PCR, 100×, 10 mL

81010 10 mL
EUR 869

dsGreen for Real-Time PCR, 100×, 5 mL

71010 5 mL
EUR 625

dsGreen for Real-Time PCR, 100×, 50 mL

91010 50 mL
EUR 3169

Virus Zika PCR kit

PCR-H434-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Virus Zika

Virus Zika PCR kit

PCR-H434-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Virus Zika

Dengue virus PCR kit

PCR-H451-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Dengue virus

Dengue virus PCR kit

PCR-H451-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Dengue virus

Chikungunya virus PCR kit

PCR-H525-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Chikungunya virus

Chikungunya virus PCR kit

PCR-H525-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Chikungunya virus

Measles Virus PCR kit

PCR-H639-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Measles Virus

Measles Virus PCR kit

PCR-H639-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Measles Virus

Mumps Virus PCR kit

PCR-H640-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Mumps Virus

Mumps Virus PCR kit

PCR-H640-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Mumps Virus

Uukuniemi virus PCR kit

PCR-V056-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Uukuniemi virus

Uukuniemi virus PCR kit

PCR-V056-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Uukuniemi virus

Reticuloendotheliosis virus PCR kit

PCR-V061-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Reticuloendotheliosis virus

Reticuloendotheliosis virus PCR kit

PCR-V061-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Reticuloendotheliosis virus

Distemper virus PCR kit

PCR-V111-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Distemper virus

Distemper virus PCR kit

PCR-V111-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Distemper virus

Pseudorabies Virus PCR kit

PCR-V123-48D 50T
EUR 425.8
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Description: An conventional PCR kit for detection of Pseudorabies Virus

Pseudorabies Virus PCR kit

PCR-V123-96D 100T
EUR 521.5
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Description: An conventional PCR kit for detection of Pseudorabies Virus

Cowpox virus PCR kit

PCR-V173-48D 50T
EUR 425.8
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Description: An conventional PCR kit for detection of Cowpox virus

Cowpox virus PCR kit

PCR-V173-96D 100T
EUR 521.5
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Description: An conventional PCR kit for detection of Cowpox virus

Akabane virus PCR kit

PCR-V267-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Akabane virus

Akabane virus PCR kit

PCR-V267-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Akabane virus

Irido virus PCR kit

PCR-V288-48D 50T
EUR 425.8
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Description: An conventional PCR kit for detection of Irido virus

Irido virus PCR kit

PCR-V288-96D 100T
EUR 521.5
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Description: An conventional PCR kit for detection of Irido virus

Mourilyan virus PCR kit

PCR-V291-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Mourilyan virus

Mourilyan virus PCR kit

PCR-V291-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Mourilyan virus

Schmallenberg virus PCR kit

PCR-V319-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Schmallenberg virus

Schmallenberg virus PCR kit

PCR-V319-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Schmallenberg virus

Ectromelia virus PCR kit

PCR-V330-48D 50T
EUR 425.8
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Description: An conventional PCR kit for detection of Ectromelia virus

Ectromelia virus PCR kit

PCR-V330-96D 100T
EUR 521.5
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Description: An conventional PCR kit for detection of Ectromelia virus

K Virus PCR kit

PCR-V365-48D 50T
EUR 425.8
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Description: An conventional PCR kit for detection of K Virus

K Virus PCR kit

PCR-V365-96D 100T
EUR 521.5
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Description: An conventional PCR kit for detection of K Virus

Sialodacryoadenitis virus PCR kit

PCR-V370-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Sialodacryoadenitis virus

Sialodacryoadenitis virus PCR kit

PCR-V370-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Sialodacryoadenitis virus

Sendai virus PCR kit

PCR-V374-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Sendai virus

Sendai virus PCR kit

PCR-V374-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Sendai virus

Junin Virus PCR kit

PCR-V388-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Junin Virus

Junin Virus PCR kit

PCR-V388-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Junin Virus

Machupo Virus PCR kit

PCR-V389-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Machupo Virus

Machupo Virus PCR kit

PCR-V389-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Machupo Virus

Lassa virus PCR kit

PCR-V390-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Lassa virus

Lassa virus PCR kit

PCR-V390-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Lassa virus

Guanarito virus PCR kit

PCR-V391-48R 50T
EUR 524.4
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Description: An conventional PCR kit for detection of Guanarito virus

Guanarito virus PCR kit

PCR-V391-96R 100T
EUR 669.4
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Description: An conventional PCR kit for detection of Guanarito virus

Furthermore, the usage of isoaaptamine resulted in a major enhance within the technology of reactive oxygen species (ROS) as well as within the disruption of mitochondrial membrane potential (MMP). The pretreatment of T-47D cells with an ROS scavenger, N-acetyll-cysteine (NAC), attenuated the apoptosis and MMP disruption induced by isoaaptamine as much as 90%, and these results have been mediated by the disruption of nuclear issue erythroid 2-related issue 2 (Nrf 2)/p62 pathway. Taken collectively, these findings steered that the cytotoxic impact of isoaaptamine is related to the induction of apoptosis and autophagy by means of oxidative stress.

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